ABSTRACT
Introduction/BackgroundCOVID-19 infection leaded to one of the greatest crises affecting the healthcare system worldwide. The aim of the current paper is to analyze the influence of previous COVID-19 infection on the perioperative outcomes of patients submitted to total pelvic exenterations for gynecological malignancies.MethodologyBetween July 2021 and April 2022 there were 38 patients submitted to pelvic exenterations for different gynecological malignancies, 11 of these cases presenting a previous history of COVID 19 infection. However, all these 11 patients developed asymptomatic or mild symptomatic disease and did not necessitate hospital admission.ResultsPatients with previous history of COVID-19 infection reported a significantly longer length of the surgical procedure (380 minutes versus 300 minutes, p=0,004), a higher intraoperative blood loss (1100 ml versus 600 ml, p=0,002) and a longer intensive care unit stay (5 days versus 2 days, p=0,001). Meanwhile, two of the patients with previous history of COVID-19 infection developed postoperative pneumonia and other three cases developed thrombotic complications while in the control group a single patient developed postoperative thrombotic complications and another one necessitated intensive care readmission due to respiratory dysfunction due to a previous history of asthmaConclusionThese data came to demonstrate that even in cases in which mild forms of COVID-19 infections have been reported, extended surgical procedures such as pelvic exenteration might be associated with a higher risk of perioperative complications.
ABSTRACT
BACKGROUND/AIM: The COVID-19 pandemic has significantly influenced the management of oncogynecologic patients in regard to time of diagnosis, to delay of treatment, therapeutic strategy and postoperative complications. The aim of the study was to investigate the impact of preoperative SARS-Cov2 infection on the postoperative outcome after debulking surgery for ovarian cancer. PATIENTS AND METHODS: Between June 2021 and September 2021, 12 patients with antecedents of COVID-19 infection and ovarian cancer were submitted to surgery at "Dr. I. Cantacuzino" Hospital, Bucharest, Romania. Their outcomes were compared to those reported in a similar group of patients submitted to surgery during the same period in the absence of COVID-19 infection. RESULTS: Although preoperative data showed no statistically significant differences between the two groups, intraoperative length and estimated blood loss were higher in the COVID-19 group and so were the postoperative complications, the most commonly encountered ones being reported by wound infection, postoperative hemoperitoneum and pneumonia. However, the differences did not reach statistical significance. CONCLUSION: Preoperative COVID-19 infection seems to slightly increase the risk of postoperative complications after debulking surgery for ovarian cancer.
Subject(s)
COVID-19 , Ovarian Neoplasms , Carcinoma, Ovarian Epithelial , Female , Humans , Ovarian Neoplasms/complications , Ovarian Neoplasms/surgery , Pandemics , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Postoperative Period , RNA, Viral , Retrospective Studies , SARS-CoV-2ABSTRACT
BACKGROUND/AIM: The aim of this study is to report a case series of three patients who developed postoperative severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) infection, although the initial tests were negative. PATIENTS AND METHODS: Between April and September 2020, three patients submitted to pancreatoduodenectomy developed SARS-CoV-2 infection; their outcomes were compared to those of a similar group in which the postoperative outcomes were uneventful. RESULTS: There were no significant differences between the two groups in terms of pre- and intraoperative outcomes; however, all of the three cases who developed SARS-CoV-2 infection postoperatively required re-admission in the intensive care unit and a longer hospital in stay. The overall mortality rate was null. CONCLUSION: Patients submitted to pancreatoduodenectomy for pancreatic head cancer who develop SARS-COV-2 infection postoperatively need a more appropriate supportive care; however, the overall mortality does not appear to increase, justifying, in this way, the continuation of programmed oncological of surgeries.